BDBM321320 US10179791, Compound 160::US10807991, Compound 160

SMILES OC(=O)CCN1CCC2(COc3cc(\C=C\c4c(Cl)cccc4Cl)ccc23)CC1

InChI Key InChIKey=FQHROTZEXOIENC-GQCTYLIASA-N

Data  9 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 321320   

TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM321320(US10179791, Compound 160 | US10807991, Compound 16...)
Affinity DataEC50:  20nMAssay Description:The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM321320(US10179791, Compound 160 | US10807991, Compound 16...)
Affinity DataEC50:  20nMAssay Description:The CHO-human-S1P5-Aeqorin assay was bought from Euroscreen, Brussels (Euroscreen, Technical dossier, Human Lysophospholid S1P5 (Edg8) receptor, DNA ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 5(Homo sapiens (Human))
Abbvie

US Patent
LigandPNGBDBM321320(US10179791, Compound 160 | US10807991, Compound 16...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human S1P5 receptor expressed in CHO cells assessed as increase in calcium flux by aequorin-derived luminescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed